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Extra info for Alcohol Intoxication and Withdrawal: Experimental Studies II

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Studies are also presented on the influence of long-term ethanol ingestion on poly A synthesis by isolated brain nuclei. MATERIALS AND METHODS Two month old male Sprague-Dawley rats were used for the experiments. For at least six weeks, half of the animals drank a 10% ethanol/water solution (v/v) while age-matched controls received water only. Both groups were provided with laboratory chow ad libitum and were maintained in the animal quarters on a 12-hour dark/12-hour light cycle. Twenty-four hours prior to experimentation, ethanol was replaced by water to ensure the absence of ethanol in these animals.

1963. Effect of adaptation to alcohol and of age on voluntary consumption of alcohol by rats, Brit. J. Nutr. 17: 453- 457. , 1972. Technique for producing an alcohol withdrawal syndrome in rats, Brain Res. 42: 550. , 1973. Technique for producing an alcohol withdrawal syndrome in rats, Isr. J. Med. Sei. 9: Suppl. 63 - 71. , 1974. butanol and clomethiazole on net movements of sodium and potassium in electrically stimulated cerebral tissue, Acta Physiol. Scand. 91: 83- 93. ALTERATION IN CEREBRAL POLYNUCLEOTIDE METABOLISM FOLLOWING CHRONIC ETHANOL INGESTION Sujata Tewari and Ernest P.

And Brawerman, G. , A po1ynue1eotide segment rieh in adenylie aeid in rapidlylabeled polyribosemal RNA eomponent of mouse sareoma 180 aseites eells. Proe. Nat. Aead. , 68: -1331-1335, 1971. ALTERATION IN CEREBRAL POLYNUCLEOTIDE METABOL15M 51 13, Lim, L. and Canellakis, E. , Adenine-rich polymer associated with rabbit reticulocyte messenger RNA. Nature 227: 710-712, 1970, 14. Darnell, J. , Wall, R. , Polyadenylic acid sequences: Role in conversion of nuclear RNA into messenger RNA. Science 174:507-510, 1971.

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